全文获取类型
收费全文 | 1350686篇 |
免费 | 117065篇 |
国内免费 | 7820篇 |
专业分类
耳鼻咽喉 | 16835篇 |
儿科学 | 43278篇 |
妇产科学 | 36790篇 |
基础医学 | 185124篇 |
口腔科学 | 36589篇 |
临床医学 | 122974篇 |
内科学 | 279470篇 |
皮肤病学 | 32051篇 |
神经病学 | 111204篇 |
特种医学 | 56443篇 |
外国民族医学 | 294篇 |
外科学 | 211779篇 |
综合类 | 34941篇 |
现状与发展 | 7篇 |
一般理论 | 419篇 |
预防医学 | 107179篇 |
眼科学 | 28783篇 |
药学 | 95830篇 |
37篇 | |
中国医学 | 3544篇 |
肿瘤学 | 72000篇 |
出版年
2018年 | 14269篇 |
2017年 | 11350篇 |
2016年 | 13511篇 |
2015年 | 15281篇 |
2014年 | 21299篇 |
2013年 | 30838篇 |
2012年 | 37864篇 |
2011年 | 40589篇 |
2010年 | 25422篇 |
2009年 | 24790篇 |
2008年 | 37464篇 |
2007年 | 39838篇 |
2006年 | 41024篇 |
2005年 | 39534篇 |
2004年 | 37367篇 |
2003年 | 36477篇 |
2002年 | 34339篇 |
2001年 | 66375篇 |
2000年 | 68252篇 |
1999年 | 56791篇 |
1998年 | 16320篇 |
1997年 | 14557篇 |
1996年 | 15479篇 |
1995年 | 16396篇 |
1994年 | 15245篇 |
1993年 | 14195篇 |
1992年 | 47224篇 |
1991年 | 45854篇 |
1990年 | 44060篇 |
1989年 | 41876篇 |
1988年 | 38820篇 |
1987年 | 38138篇 |
1986年 | 35909篇 |
1985年 | 34677篇 |
1984年 | 26356篇 |
1983年 | 22078篇 |
1982年 | 13822篇 |
1981年 | 12421篇 |
1980年 | 11673篇 |
1979年 | 23533篇 |
1978年 | 17028篇 |
1977年 | 14347篇 |
1976年 | 13150篇 |
1975年 | 13712篇 |
1974年 | 16090篇 |
1973年 | 15400篇 |
1972年 | 14184篇 |
1971年 | 13043篇 |
1970年 | 11878篇 |
1969年 | 11118篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
101.
Viakhireva I. Musatova E. Bessonova L. Shcherbatyuk Y. Korobkov S. Zhikriveckaya S. Sofronova Ya. Mironova I. Khmelkova D. Konovalov F. Baranova A. Pomerantseva E. Skoblov M. 《Familial cancer》2020,19(3):241-246
Familial Cancer - Despite the acceptance of NextGen sequencing as a diagnostic modality suitable for probands and carriers of Mendelian diseases, its efficiency in identifying causal mutations is... 相似文献
102.
Objective
It is useful for reviewers of economic evaluations to assess quality in a manner that is consistent and comprehensive. Checklists can allow this, but there are concerns about their reliability and how they are used in practice. We aimed to describe how checklists have been used in systematic reviews of health economic evaluations.Methods
Meta-review with snowball sampling. We compiled a list of checklists for health economic evaluations and searched for the checklists’ use in systematic reviews from January 2010 to February 2018. We extracted data regarding checklists used, stated checklist function, subject area, number of reviewers, and issues expressed about checklists.Results
We found 346 systematic reviews since 2010 that used checklists to assess economic evaluations. The most common checklist in use was developed in 1996 by Drummond and Jefferson, and the most common stated use of a checklist was quality assessment. Checklists and their use varied within subject areas; 223 reviews had more than one reviewer who used the checklist.Conclusions
Use of checklists is inconsistent. Eighteen individual checklists have been used since 2010, many of which have been used in ways different from those originally intended, often without justification. Different systematic reviews in the same subject areas would benefit from using one checklist exclusively, using checklists as intended, and having 2 reviewers complete the checklist. This would increase the likelihood that results are transparent and comparable over time. 相似文献103.
104.
目的 探讨肝动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)术前天冬氨酸氨基转移酶与淋巴细胞比值(aspartate aminotransferase to lymphocyte ratio index,ALRI)在原发性肝癌并门脉癌栓(primary liver cancer-portal vein tumor thrombosis,PLC-PVTT)患者预后预测中的价值。方法 选取2013年11月21日至2018年8月22日于广西医科大学附属肿瘤医院接受TACE治疗的175例PLC-PVTT患者为研究对象。采用时间依赖性ROC曲线确定ALRI的最佳临界值。采用Cox 回归模型分析总生存期(overall survival,OS)的独立预测因素,Kaplan-Meier法计算生存率。结果 ROC曲线显示,ALRI的最佳临界值为49.37,对应曲线下面积为0.71。Kaplan-Meier分析显示,ALRI>49.37的患者OS较ALRI≤49.37的患者短(P=0.003)。Cox 回归分析结果显示,ALRI>49.37、行1次以上TACE治疗、Child-Pugh分级B级、凝血酶原时间≥13 s是患者TACE术后OS的独立危险因素(均P<0.05)。结论 TACE术前ALRI>49.37是PLC-PVTT患者OS的独立危险因素。 相似文献
105.
106.
Edward De Wolf Karel Claes Casper E. Sommeling Dries Opsomer Mario Cherubino Salvatore Vieni Stan Monstrey Salvatore D’Arpa 《The journal of sexual medicine》2019,16(7):1111-1117
IntroductionThe free radial forearm (FRFA) flap is universally still considered as the gold standard technique in penile reconstruction. Typically, a considerably large flap is required, often involving almost the entire circumference of the forearm. Partial necrosis may occur at the distal-most (dorsoradial) part of the flap as a result of insufficient perfusion.AimTo describe a new technique using the posterior interosseous artery (PIOA) to supercharge FRFA phalloplasty.MethodsIn a 12-month period, all patients having FRFA flap phalloplasty were enrolled. Perioperative, after complete flap dissection, an indocyanine green perfusion scan was performed. In case of insufficient perfusion at the distalmost part of the flap, a supramicrosurgical anastomosis was performed between the FRFA pedicle and the PIOA (artery only).Main Outcome MeasuresStudied outcomes included the rate of marginal necrosis, surgical time, postoperative posterior interosseous nerve damage and urethral complications (fistula, stenosis or necrosis).ResultsA total of 27 FRFA flap phalloplasties was performed. Anastomosis of the PIOA was needed in 15 cases. No marginal necrosis was observed in these cases. There were no cases of postoperative posterior interosseous nerve damage. There were no significant differences in urethral complications (fistula, stenosis or necrosis) between the 2 groups.Clinical ImplicationsIn selected cases where insufficient perfusion of the dorsoradial part of the flap is present, patients may benefit from arterial supercharging to prevent postoperative marginal necrosis.Strength & LimitationsStrengths include a single surgeon, thus lending continuity of skill and technique, a consecutive series, and 100% short-term follow-up. Limitations include single institution series and a limited number of patients.ConclusionArterial supercharging is effective in improving perfusion of large FRFA flaps used in phalloplasty when dorsoradial hypoperfusion is detected on an indocyanine green perfusion scan. It is a technically challenging addition to the standard technique because of the small size of the vessels, the close relationship between the PIOA and the posterior interosseous nerve, and the vulnerability of the newly constructed intra-flap anastomosis.De Wolf E, Claes K, Sommeling CE, et al. Free Bipedicled Radial Forearm and Posterior Interosseous Artery Perforator Flap Phalloplasty. J Sex Med 2019;16:1111–1117. 相似文献
107.
N. Subramaniam D. Balasubramanian S. Murthy P. Rathod S. Vidhyadharan K. Thankappan S. Iyer 《International journal of oral and maxillofacial surgery》2019,48(2):152-156
According to the eighth edition of the AJCC Cancer Staging Manual (AJCC8), a depth of invasion (DOI) >10 mm is classified as pT3, representing a locally advanced tumour requiring postoperative radiotherapy (PORT). When node-negative, however, evidence regarding whether PORT improves loco-regional control or survival is unclear. To clarify this, two cohorts of patients were studied: (1) patients classified as pT3N0 by the seventh edition of the AJCC manual (AJCC7), with DOI >10 mm and a tumour diameter >4 cm (17 patients who received PORT), and (2) patients classified as pT1N0 and pT2N0 by AJCC7, with DOI >10 mm and a tumour diameter <4 cm (55 patients who did not receive PORT). Loco-regional control and survival were analysed. PORT was found not to impact overall survival or disease-free survival. It was also found not to impact local, regional, or distant recurrence. Although the two subsets of patients considered here (DOI >10 mm with tumour diameter below or above 4 cm) were previously distinct, they are both considered pT3 in AJCC8. Data from this study indicate that the routine administration of PORT to patients with a DOI >10 mm may not be warranted in the absence of other risk features such as nodal disease or close margins. 相似文献
108.
109.
110.
Milan Milojevic Patrick W. Serruys Joseph F. Sabik David E. Kandzari Erick Schampaert Ad J. van Boven Ferenc Horkay Imre Ungi Samer Mansour Adrian P. Banning David P. Taggart Manel Sabaté Anthony H. Gershlick Andrzej Bochenek Jose Pomar Nicholas J. Lembo Nicolas Noiseux John D. Puskas Arie Pieter Kappetein 《Journal of the American College of Cardiology》2019,73(13):1616-1628